Key Components
Main Unit - Core processing chamber for granulation & drying.
Air Inlet System - Provides controlled, filtered air flow.
Exhaust & Dust Collection System - Ensures clean discharge.
Secondary Dust Removal System - Enhances environmental compliance.
Spray System - Precisely atomizes binder solution.
Explosion-proof System - Ensures safety for solvent-based processes.
Automated Control System - Enables precise process regulation.
This system delivers efficient drying, uniform granule formation, and high productivity while meeting cGMP and industrial safety standards.
Key Features
Multi-functional Integration
Combines mixing, drying, spray granulation, and coating in a single unit.
Converts liquid feed directly into granules in one step.
Capable of rapid drying, powder processing, and granule production.
Closed & Hygienic Design
Operates under sealed negative pressure for dust-free processing.
Smooth internal surfaces, no dead corners, ensuring easy cleaning and compliance with cGMP standards.
Optimized workflow reduces manual labor and prevents cross-contamination.
Eco-friendly & Cost-efficient
Uses liquid feed as a binder, significantly reducing alcohol consumption.
Lowers production costs while enabling small-dose, sugar-free, or low-sugar formulations.
Fully Automated Control
PLC-based automation allows customizable process settings.
Real-time monitoring & data logging for reliable batch records.
Precise and repeatable parameters ensure consistent granule quality and scalability for multi-formula production.
Working Principle
The fluidized bed granulator and dryer operates as follows:
Automatic Loading
The material container is either pushed into the main unit or directly loaded.
A negative pressure airflow generated by the exhaust fan draws materials into the processing chamber through an automatically controlled feed valve and pipeline.
Sealing & Startup
Airflow & Filtration System
Air is drawn by a variable-speed induced draft fan, passing through:
Primary filter to Surface cooler to Moisture separator to Medium-efficiency filter to Heat exchanger to HEPA filter to Air distribution plate.
Filtered air enters the fluidized bed granulation chamber, fluidizing and drying the material.
Temperature & Airflow Control
The heating system adjusts inlet air temperature automatically.
A pneumatic-controlled air damper regulates the hot/cold air ratio, maintaining precise temperature control.
An adjustable automatic inlet valve controls airflow volume, with sensors monitoring flow rate, temperature, and humidity.
Spray Granulation Process
Liquid binder is delivered via a peristaltic pump to the spray nozzle, where compressed air atomizes it into the droplets.
The mist coats fluidized powder particles, forming granules while hot air simultaneously dries them.
Powder Recovery & Filter Cleaning
Fine particle carried upward by airflow are captured by filter bags.
A cyclical bag-shaking mechanism(alternating left/right) dislodges adhered powder, which falls back for reprocessing.
Ensures continuous operation without clogging.
Exhaust & Secondary Filtration
Discharged air passes through a secondary dust removal system for final filtration.
Cleaned air is expelled via a silenced exhaust fan, meeting environmental standards.
Discharge & Post-processing
After drying/granulation, the chamber unseals.
The material container is either:
Connected to a transfer system for direct discharge, or
Emptied via vacuum conveying to a sizing mill.
Prevents dust exposure and cross-contamination, ensuring cGMP compliance.
This integrated design ensures efficient, dust-free, and repeatable granulation, drying, and coating in compliance with pharmaceutical and food industry standards.
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